**Background:** Terazosin (TZ) and closely related α1-adrenergic receptor antagonists (doxazosin [DZ] and alfuzosin [AZ]) enhance glycolysis and reduce neurodegeneration in animal models. Observational evidence in humans from several databases …
**Importance:** Parkinson disease (PD) is a common neurodegenerative disease. A treatment that prevents or delays development of PD is a critical unmet need. Terazosin and closely related drugs were recently discovered to enhance glycolysis and …
Hydroxychloroquine combined with azithromycin has been investigated for activity against coronavirus disease 2019 (COVID-19), but concerns about adverse cardiovascular (CV) effects have been raised. This study evaluated claims data to determine if …
**Introduction:** We identified patterns of postoperative pain and opioid consumption and associated factors following ureteroscopy for kidney stones by acquiring real-time data through automated text messages. **Methods:** Adult patients undergoing …
Parkinson's disease (PD) is a common neurodegenerative disease that lacks therapies to prevent progressive neurodegeneration. Impaired energy metabolism and reduced ATP levels are common features of PD. Previous studies revealed that terazosin (TZ) …
**BACKGROUND:** Monitoring prescription drug utilization is important for both drug safety and drug marketing purposes. However, access to utilization data is often expensive, limited and not timely.
**OBJECTIVES:** To demonstrate and validate the …