A pilot to assess target engagement of terazosin in Parkinson's disease

BACKGROUND: Impaired brain energy metabolism is a key feature of Parkinson's disease (PD). Terazosin (TZ) binds phosphoglycerate kinase 1 and stimulates its activity, which enhances glycolysis and increases ATP levels. Preclinical and epidemiologic …

Patterns of medication use and imaging following initial diagnosis of sarcoidosis